UPDATED ON: August 10, 2016
SlickRun is a free floating command line utility for Windows that gives you almost instant access to any program or website
SlickRun allows you to create command aliases (known as MagicWords), so C:Program FilesOutlook Expressmsimn.exe becomes MAIL.
Enter a web URL into SlickRun and it will launch your browser and navigate to the specified address. Run multiple programs in a few keystrokes, jot a note, look up a definition... SlickRun is the most natural way to interact with your computer.